Achaogen Announces Multiple Plazomicin Presentations at European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)


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April 10, 2018 at 8:01 AM EDT

Achaogen Announces Multiple Plazomicin Presentations at European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

-- Study findings support the potential for plazomicin to address difficult-to-treat infections, including those caused by carbapenem-resistant Enterobacteriaceae --

SOUTH SAN FRANCISCO, Calif., April 10, 2018 (GLOBE NEWSWIRE) -- Achaogen, Inc. (NASDAQ:AKAO), a late-stage biopharmaceutical company developing innovative antibacterials addressing multi-drug resistant (MDR) gram-negative infections, today announced four upcoming presentations on plazomicin at the 28th European Congress of Clinical Microbiology and Infectious Disease (ECCMID). The Company and its collaborators will deliver one mini-oral and three poster presentations at the event being held in Madrid, Spain from April 21 to 24, 2018.

Mini-Oral Presentation

Title:Plazomicin versus Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI): An Analysis by Complicating Factor in the EPIC Study, Nowicki et al (Oral flash #O0419)
Session:

OF081: Snapshot on pre-registration clinical trials
Sunday, April 22, 2018 from 11:30am - 12:30pm CET

Poster Presentations

Title:

Plazomicin is Associated with Fewer Post-Baseline Infectious Complications Compared with Colistin in Patients with Serious Infections due to Carbapenem-Resistant Enterobacteriaceae (CRE): Results from the Randomized, Controlled CARE Study, Pontikis et al (Poster #P0284)
Session:

PS018: Clinical trial experience - new antibacterial agents
Saturday, April 21, 2018 from 3:30 - 4:30pm CET
  
Title:

Plazomicin Activity Against Enterobacteriaceae Collected from Europe, Latin America, and Asia-Pacific during 2016, Including Those with Aminoglycoside and Beta-Lactam Resistance Mechanisms, Castanheira et al (Poster #P0093)
Session:

PS006: Activity of new or re-purposed non-beta-lactam drugs against Gram-negatives
Saturday, April 21, 2018 from 3:30 - 4:30pm CET
  
Title:In Vitro Activity of Plazomicin Against Klebsiella spp. Blood Isolates, Liste et al (Poster #P0095)
Session:

PS006: Activity of new or re-purposed non-beta-lactam drugs against Gram-negatives
Saturday, April 21, 2018 from 3:30 - 4:30pm CET
  

The abstracts can be accessed through the ECCMID website. Following the meeting, the presentation slides and posters will be available on the Achaogen website.

About Achaogen
Achaogen is a late-stage biopharmaceutical company passionately committed to the discovery, development, and commercialization of innovative antibacterial treatments for MDR gram-negative infections. Achaogen is developing plazomicin, its lead product candidate, for the treatment of serious bacterial infections due to MDR Enterobacteriaceae, including carbapenem-resistant Enterobacteriaceae. The Food and Drug Administration has granted plazomicin Breakthrough Therapy designation for the treatment of bloodstream infections caused by certain Enterobacteriaceae in patients who have limited or no alternative treatment options. Achaogen's plazomicin program has been funded in part with Federal funds from the Biomedical Advanced Research and Development Authority (BARDA), Office of the Assistant Secretary for Preparedness and Response, Office of the Secretary, Department of Health and Human Services, under Contract No. HHSO100201000046C. The Company's second product candidate C-Scape, an orally-administered beta-lactam/beta-lactamase inhibitor combination, is funded in part with Federal funds from BARDA. Achaogen has other programs in early and late preclinical stages of development focused on MDR gram-negative infections and additional disease areas. All product candidates, including plazomicin, are investigational and have not been approved for commercialization. For more information, please visit www.achaogen.com.

Forward-Looking Statements
This press release contains forward-looking statements. All statements other than statements of historical facts contained herein are forward-looking statements reflecting the current beliefs and expectations of management made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, including, but not limited to, Achaogen's expectations regarding potential regulatory approval of plazomicin and Achaogen's commercial objectives. Such forward-looking statements involve known and unknown risks, uncertainties and other important factors that may cause Achaogen's actual results, performance or achievements to be materially different from any future results.  Such risks and uncertainties include, among others, the uncertainties inherent in the preclinical and clinical development process and the risks and uncertainties of the regulatory approval process. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to Achaogen's business in general, see Achaogen's current and future reports filed with the Securities and Exchange Commission, including its Annual Report on Form 10-K filed on February 27, 2018. Achaogen does not plan to publicly update or revise any forward-looking statements contained in this press release, whether as a result of any new information, future events, changed circumstances or otherwise.

Source: Achaogen, Inc.

          
Investor Contact:        Media Contact:
Ashley R. Robinson        Denise T. Powell
LifeSci Partners, LLC        Red House Consulting, LLC
arr@lifesciadvisors.com         dpowell@achaogen.com